Protein levels could be key to infertility
Researchers believe female infertility and miscarriage could be caused by the malfunction of a single protein
Researchers believe female infertility and miscarriage could be caused by the malfunction of a single protein
Researchers believe female infertility and miscarriage could be caused by the malfunction of a single protein. Female infertility and pregnancy loss could be the result of faulty levels of a protein which regulates fluid balance in parts of the womb according to new research.
A team of experts from Imperial College London took samples from the womb lining of more than 100 women and found women with unexplained infertility had high levels of the enzyme SGK1 and those who had experienced miscarriage had low levels.
Much higher levels of the protein disrupted the manufacture of proteins in the fertilised egg and also the womb environment, causing infertility.
With around one in eight known pregnancies ending in miscarriage and recurrent preganncy loss affecting approximately one in 100 women, the findings published in Nature Medicine could lead the medical community one step closer to finding a treatment.
'In the future, we might take biopsies of the womb lining to identify abnormalities that might give a higher risk of pregnancy complications, so that we can start treating [women] before they get pregnant,' says researcher Dr Madhuri Salker.
Professor Richard Fleming, of the Glasgow Centre for Reproduction Medicine, says: 'To have something as clear as this, with a specific enzyme, is great. It is giving us something to focus on.'
Marie Claire Newsletter
Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!
-
Your mouth-gut axis is way more important than you think – how poor oral hygiene can impact your health
This one's worth reading.
By Abbi Henderson
-
Leopard print activewear perfectly balances style and substance - MC UK Editors share their 8 top picks
Transition from the gym to brunch dates with no need for an outfit change.
By Amelia Yeomans
-
My body regimen is just as important to me as my skincare routine and these are my two essential products
Say hello to beautifully soft skin
By Lollie King